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CPSA Digest 2002

Emerging Standards for Drug Discovery and Development:
Perspectives on Technology, Strategy and Relationships

October 8-10, 2002

CPSA Digest 2002

Overview
Day 1: Proceedings | Plenary
Day 2: Proceedings
Day 3: Proceedings

CPSA 2002 Sponsors

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Proceedings

Day 1 - Tuesday, October 8, 2002



Overview

Objectives/Format/Opening Remarks

Program Chair:Kenneth L. Morand, Procter & Gamble Pharmaceuticals, Mason, Ohio



TuOA
Plenary

Trends in the Economics of Pharmceutical Innovation: Cost, Time, and Risk

Joseph A. DiMasi, Director of Economic Analysis
Tufts Center for the Study of Drug Development



TuOB
Genomics/Post Genomics Trends

Discussion Leader: Steven A. Hofstadler, IBIS Therapeutics

Applying Antisense Technology for Functional Genomics and Drug Discovery

Brett Monia, ISIS Pharmaceuticals

High Throughput Genotyping Using Illumina's Bead Array Technology

David Barker, Illumina, Inc.

Modeling of Alternative Splicing in Mammalian Genomes Using Compugen's LEADs Technology

Alon Amit, Compugen

Roundtable Discussion 1



TuOC
Vendor/Exhibitor Session:
Sample Preparation & Chromatography

The Autogizer - An Automated Homgenization and Washing System

Ken Workowski, Tomtec

Protein Precipitation Demonstrated in Microwell Filter Format for LC-MS/MS Bioanalytical Sample Preparation

Asha A. Oroskar, Orochem Technologies, Inc.

Advances in Low Volume, High-Throughput Turbulent Flow Chromatography, Including Parallel Approaches

Joseph M.Di Bussolo, Cohesive Technologies, Inc.

Development of a Novel HPLC Column Technology for Peptide Mapping and Proteomics

Tivadar Farkas, Phenomenex, Inc.

Automated Parallel Separations for LC/MS

Michael Sabatino, LEAP Technologies

A Microfluidic Device for High Throughput Separations

Hugh McManus, Nanostream, Inc.

The MS4, A New Highly Flexible HPLC Separations Module for Multidimensional Separations

Kerry Nugent, Michrom BioResources, Inc.

2-D Capillary/Nano LC as a Front-End Separations Tool for MS Proteomics

Herb Schwartz, Dionex Corporation

New Developments in LC and LC/MS for Enhancing Drug Discovery and Development Programs

Gordon S. Hunter, Gilson, Inc.

Roundtable Discussion 2



TuOD
Instrumentation for Protein Characterization - Emerging Trends in Proteomic Analysis

Discussion Leader: Ioannis A. Papayannopoulos, Applied BioSystems

The Role of Complete de novo Peptide Sequencing in Protein Characterization

Al Yergey, National Institutes of Health

Isotope Coded Reduction off of Chromatographic Support

Richard S. Johnson, Amgen, Inc.

Unraveling Signaling Pathways Using Mass Spectrometry

TuOD3: Roland S. Annan, GlaxoSmithKline

Roundtable Discussion 3



TuOE
Metabonomics

Discussion Leaders: John P. Shockcor, Metabometrix Ltd.

Unusual Clinical Applications of Metabonomics

John P. Shockcor, Metabometrix Ltd.

Potential of LC/MS(MS) for Metabonomic Studies

Robert S. Plumb, Waters Corporation

Rapid Metabolite Identification by NMR - Applications and Innovations

David Wishart, CHENOMIX, Inc.



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