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Overview
The Symposium on Chemical and Pharmaceutical Structure Analysis (CPSA)
is focused on connecting industry needs with innovative technologies
and solutions. This 3-day meeting is structured to promote interaction
and discussion among audience members, speakers, poster presenters and
vendors. The opportunity for interactive sessions and discussion is
a distinguishing characteristic of this event.
The symposium begins with an understanding of the industry related
issues and needs and a progression may be expected to proceed as
follows. An analysis of trends yields insight into the issues. A vendor
with a new technology is identified that may help solve a need.
Evaluation and assessment of this technology are conducted. Integration
of the technology is begun and experiences are shared among different
users, either within the same company and/or between companies. The
end result is to reach consensus and satisfy an identified need within
the pharmaceutical development industry.
A term used at Procter & Gamble is "Connect and Develop."
The technology is out there. Pharmaceutical R&D has developed a strategy. These
two items are connected via relationships initiated and/or strengthened
at
this symposium. Three key factors to the success of the symposium
are
discussion, understanding and tangible solutions. By the end of the
3
days at CPSA, the goal is to develop a better strategy than the one
drafted prior to arriving here. Each individual is expected to gain
some
tangible solution that they can take back to their company and
implement.
Expressed in another way, the goal of the CPSA is to provide for
incubation of ideas for accelerated drug discovery and development.
The program has been intentionally designed to allow for maximum interaction
and discussion so that this goal can be achieved.
The format of the CPSA consists of:
- Symposia (podium & poster) - Industry issues and needs - Analysis strategies - Performance benchmarks
- Moderated Roundtables - Commercial technology - Mainstream applications - Analysis trends
- Exhibition - Vendor products and solutions
The scientific program is arranged around themed modules, one discussed per day:

Day One - Target Identification & Validation
- Genomics/Post-Genomics Trends
- Instrumentation for Protein Characterization - Emerging Trends in Proteomic Analysis
- Metabonomics
- Vendor/Exhibitor Session-Sample Preparation & Chromatography
- Poster Session
Day Two - Lead Identification & Optimization
- Advances in Microfluidics Technology
- The Value of the Corporate Compound Collection - Protecting Your Investment
- Preclinical Lead Optimization - Are We Making a Difference?
- Emerging Technologies for Drug Discovery and Development
- Vendor/Exhibitor Session - Mass Spectrometry and Data Management
- Poster Session/Social Hour
Day Three - Preclinical Development
- Data Management in a High-Throughput Analysis Environment
- Why Does Method Development Take So Long?
- Poster Session Reviews
- In-Source, Out-Source - What Do Pharmaceutical Companies do for Bioanalytical Support?
- Crystal City Guideline Review
This event begins with the plenary lecture for the 5th Annual Symposium
on Chemical and Pharmaceutical Structure Analysis, "The Economics of
Pharmaceutical Innovation: Trends in Costs, Risks and Returns"
by Joseph A. DiMasi, Ph.D., Director of Economic Analysis at the Tufts Center
for the Study of Drug Development.
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