Proceedings

Day 2 - Tuesday, September 23, 2003

Using Comprehensive Metabolomics to Determine and Classify the Mode(s) of Action of New Chemical Entities and their Relative Toxicity Risks

Automated Approaches to the Detection and Characterization of Pharmaceutical Metabolites by the Application of MS/MS Software Algorithms

New Methods for Rapid Analysis of Radiocarbon-labeled Drugs by Accelerator Mass Spectrometry

Roundtable Discussion

A High Throughput LC-MS-MS Method for Screening Glutathione Conjugations Using Exact Mass Neutral Loss

Reactive Intermediates in Drug Metabolism: Tools and Toxicology

Mechanistic Investigation Into the Formation of Reactive Metabolites in Drug Discovery and Development

Roundtable Discussion

Strategies for Predictive Library Rehearsal, Design and QC that Deliver High Quality Combinatorial Libraries

Repository Compound Stability and Quality Studies in Support of Lead Discovery

Design and Implementation of Technologies to Purify 10,000 Samples Per Month

High Throughput Liquid Chromatography Systems for Compound Library Screening

Roundtable Discussion

Visual Basic for Applications (VBA): A Powerful Tool for Automated Data Processing

Data Transformation and Processing in CYP-Inhibition HTS Assays

Enabling Collaboration Across Multiple Disciplines to Accelerate Drug Discovery

Bringing Biology to Proteomics: Integration with Functional Genomics

Roundtable Discussion

Drug Discovery Technologies & Applications

Automated Method Development for Solid Phase Extraction in an Online SPE/LC/MS System

Plasma Protein Binding Determination By Equilibrium Dialysis Based On LC/MS/MS Peak Area Ratios In Support Of Drug Discovery

Overview of Isothermal Titration Calorimetry and Differential Scanning Calorimetry

High Throughput Applications of Multiplexed Capillary Electrophoresis with Absorbance Detection in Drug Discovery and Development

Sustained Carryover Elimination in LC/MS Drug Analysis

Parallel Liquid Chromatography for High Throughput ADMET Profiling

Increased Throughput and Separation in Nano-HPLC-MS Using a Dual-Gradient Nano-HPLC System and Monolithic Columns

High Throughput Microfluidic HPLC-UV System

Drug Discovery Technologies & Applications

The Sensitivity Increase with IONICS EP 10+ System

A Novel MS Based Metabonomic Approach to the Determination of Biomarkers of Drug Toxicity

Accurate and MSn Mass Spectra in Combination with Smart Processing Tools for Metabolite Identification

A Practical Cryodetector Mass Spectrometer for High Sensitivity Detection and Energy Resolution at High Mass

The Finnigan TSQ Quantum Triple Quadrupole Mass Spectrometer Product Line: High Performance Quantitation at Unit and Enhanced Mass-Resolution with Accurate Mass Measurement Capabilities

Application of MALDI-MS Imaging Software for Small Molecule Profiling in Tissue Samples

A Quick Overview of Novatia's Metlab Software

Using ChemAnalytics to Support the Drug Discovery Process

Automated Capture, Cataloging and Re-use Platform for Data Management

A Flexible Asset Management Program for Drug Discovery Instrument Acquisition

Poster Sessions

6. Structure Identification
7. Bioanalysis and ADME Screening
8. Pharmaceutical Profiling
9. Data Analysis
10. New Applications, Methodologies & Technologies