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CPSA Digest 2003

From Proteomics to the Pill:
New Initiatives in Proteomics, Drug Discovery, and Development

September 22-24, 2003

CPSA Digest 2003

Day 1: Proceedings | Plenary
Day 2: Proceedings
Day 3: Proceedings

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Day 3

WeOC4

Gaining Additional Value from NuGenesis Archive for Scientific Knowledge Management

Joel Swerdel, Bristol-Myers Squibb


Information Challenges in Analytical R&D

  • Need to work with many groups and areas within the company
  • Need to share information easily
  • Need to get information from many sources and among departments
  • Need to separate "wheat from chaff" (information overload exists, limited time to review this information, need a concise summary quickly and easily)

System Requirements

  • Easy Information Submission
    • Get chemists to input information voluntarily when it is easy to do.
  • Preferred Information Notification
    • If you are an HPLC chemist, have little interest in looking at NMR data or a formulation report for projects you are not involved with; then develop a view of information that is of interest and filter away the rest.
  • Connections to Other Information Sources
    • Not just another computer system but THE computer system; submit information directly or pull from a multitude of sources.
  • Discussion Forum
    • People submit a document and put it out for questions, "Does anyone have any ideas about this problem?"

Analytical Knowledge Management Initiative AKMI

  • Developed in-house using existing tools (ASP and JavaScript)
  • Web-based front end
  • Oracle and Documentum back end


Click on image for larger view

Features of AKMI

  • Consistent "look and feel"
    • Keep the screen as "clean" as possible; apply standards from the web as people are used to. Log-in to the system brings email as well as desired preferences. Not GMP-compliant system but information sharing system is "as open as possible."
  • Setting Preferred Topics
    • Can send preferences to colleagues; useful if starting a group.
  • History Page
    • Retrieval history and submission history.
  • Information Submission
    • Goal is minimum amount of effort to submit a document to encourage usage. Put in a file, title, author filled in automatically, then topic of interest (categories). Quick-text is for a quick note to input directly and submit to a group of colleagues.
  • Inserting Rich Text
    • A tool is supplied that creates an HTML document without having to know HTML; acts like a word processor in its ability to add fonts, colors, tables and pictures.
  • Information Search
    • Topics that you are interested in are always listed at the top of a page
  • Saving Queries
  • Automatic Notification

NuGenesis Archive as Web Crawler

  • This system could not be just another information source.
  • Needed to be THE information source.
  • NuGenesis Archive provided an easy way to search other information sources, find valuable new information and include it in AKMI.
  • Today: NuGenesis searches department file systems.
  • Tomorrow: NuGenesis will search Documentum-based document repositories.

Conclusion

  • Scientists need to get at information quickly and easily.
  • Scientists DO NOT want more computer systems to complicate their lives, they want less.
  • With the glut of information received each day by scientists, there needs to be a way to bring the most important information to the top of the pile.
  • NuGenesis Archive is a valuable tool to help bring data from many sources into one central location.


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