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Day 3
Vendor/Exhibitor Session
Apex-QTM Hybrid FTMS: Unique Power for Complex Proteomics
Victor Fursey, Bruker Daltonics Inc.
The APEX-Q platform combines a Q-q- "front-end" and a high field FTMS
magnet (7, 9.4 or 12 Tesla) for the ultimate resolution proteomics mass
spectrometer. This novel combination increases the superb resolution and
mass accuracy of FTMS by using the latest proprietary high-field magnet
technology, while adding efficient precursor mass selection and
collision induced dissociation in a conventional Q-q "front end" for
on-the-fly data-dependent MS/FTMS fragmentation or selected accumulation
of LC-separated protein digests.
The high-field APEX-Q can deliver sub-ppm mass accuracy, enormous
resolving power for peptide mixtures, wide bandwidth detection, high
dynamic range, and fast automated data-dependent MS/MS for detailed
proteome characterization when coupled on-line to liquid chromatography.
With the APEX-Q, the life science researcher now has access to automated
data dependent MS/MS functionality operating with dynamic exclusion
lists, inclusion lists and other "smart" MS/MS proteomics protocols with
the added benefit of FTMS caliber performance.
The Figure shown above illustrates data dependent Nano-LC-FTMS/MS with
accurate mass.
Additional features include:
- MALDI and ESI / nanospray interfaces are possible with "on the fly" 30
sec switchover time using CombiSource
- Unique ion enrichment for MS and MS/MS ions is performed using Qq
- Enhanced problem solving with wide dynamic range
- New software for straight-forward usage and compatability with other
- Bruker MS systems/data
Contact Linformation
Bruker Daltonics
40 Manning Road
Bellerica, MA 01821
978-663-3660
978-667-5993 Fax
www.bdal.com/apexq.html
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